Protective effects against tumors and infection by interleukin-27 through promotion of expansion and differentiation of hematopoietic stem cells into myeloid progenitors

Interleukin (IL)-27 is a multifunctional cytokine that belongs to the IL-6/IL-12 family and has potent antitumor activity through various mechanisms. Our novel findings indicate that IL-27 directly acts on hematopoietic stem cells and promotes their expansion and differentiation into myeloid progeni...

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Publicado no:Oncoimmunology
Main Authors: Orii, Naoko, Mizoguchi, Izuru, Chiba, Yukino, Hasegawa, Hideaki, Ohashi, Mio, Xu, Mingli, Nagai, Taro, Ochiai, Nakaba, Mochizuki, Yuki, Owaki, Toshiyuki, Yoshimoto, Takayuki
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927478/
https://ncbi.nlm.nih.gov/pubmed/29721372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1421892
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