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Prediction of Chemical Respiratory and Contact Sensitizers by OX40L Expression in Dendritic Cells Using a Novel 3D Coculture System

The use of animal models in chemical safety testing will be significantly limited due to the recent introduction of the 3Rs principle of animal experimentation in research. Although several in vitro assays to predict the sensitizing potential of chemicals have been developed, these methods cannot di...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Mizoguchi, Izuru, Ohashi, Mio, Chiba, Yukino, Hasegawa, Hideaki, Xu, Mingli, Owaki, Toshiyuki, Yoshimoto, Takayuki
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543289/
https://ncbi.nlm.nih.gov/pubmed/28824649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00929
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