Mitochondrial nicotinamide adenine dinucleotide reduced (NADH) oxidation links the tricarboxylic acid (TCA) cycle with methionine metabolism and nuclear DNA methylation

Mitochondrial function affects many aspects of cellular physiology, and, most recently, its role in epigenetics has been reported. Mechanistically, how mitochondrial function alters DNA methylation patterns in the nucleus remains ill defined. Using a cell culture model of induced mitochondrial DNA (...

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Bibliografische gegevens
Gepubliceerd in:PLoS Biol
Hoofdauteurs: Lozoya, Oswaldo A., Martinez-Reyes, Inmaculada, Wang, Tianyuan, Grenet, Dagoberto, Bushel, Pierre, Li, Jianying, Chandel, Navdeep, Woychik, Richard P., Santos, Janine H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2018
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Short Reports
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927466/
https://ncbi.nlm.nih.gov/pubmed/29668680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2005707
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