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Oxidative DNA Damage Induced by a Metabolite of 2–Naphthylamine, a Smoking‐related Bladder Carcinogen

2‐Naphthylamine (2‐NA), a bladder carcinogen, is contained in cigarette smoke. DNA adduct formation is thought to be a major cause of DNA damage by carcinogenic aromatic amines. We have investigated whether a metabolite of 2‐NA, 2‐nitroso‐1‐naphthol (NO‐naphthol) causes oxidative DNA damage, using (...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Ohnishi, Shiho, Murata, Mariko, Kawanishi, Shosuke
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927071/
https://ncbi.nlm.nih.gov/pubmed/12149138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2002.tb01314.x
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