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Oxidative DNA Damage Induced by an N‐Hydroxy Metabolite of Carcinogenic 4‐Dimethylaminoazobenzene
Formation of adducts has been considered to be a major causal factor of DNA damage by carcinogenic aminoazo dyes. We investigated whether a metabolite of hepatocarcinogenic 4‐dimethylaminoazobenzene (DAB) can cause oxidative DNA damage or not, using (32)P‐5′‐end‐labeled DNA fragments. The DAB metabo...
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| Veröffentlicht in: | Jpn J Cancer Res |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Publishing Ltd
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5926586/ https://ncbi.nlm.nih.gov/pubmed/11173540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2001.tb01043.x |
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