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Oxidative DNA Damage Induced by an N‐Hydroxy Metabolite of Carcinogenic 4‐Dimethylaminoazobenzene

Formation of adducts has been considered to be a major causal factor of DNA damage by carcinogenic aminoazo dyes. We investigated whether a metabolite of hepatocarcinogenic 4‐dimethylaminoazobenzene (DAB) can cause oxidative DNA damage or not, using (32)P‐5′‐end‐labeled DNA fragments. The DAB metabo...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Ohnishi, Shiho, Murata, Mariko, Degawa, Masakuni, Kawanishi, Shosuke
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926586/
https://ncbi.nlm.nih.gov/pubmed/11173540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2001.tb01043.x
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