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Germline mutations in the alternative pathway of complement predispose to HELLP syndrome
BACKGROUND. HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome is a severe variant of hypertensive disorders of pregnancy affecting approximately 1% of all pregnancies, and has significant maternal and fetal morbidity. Previously, we showed that upregulation of the alternative pat...
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| 出版年: | JCI Insight |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5926944/ https://ncbi.nlm.nih.gov/pubmed/29563339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99128 |
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