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Functional Polymorphism of the Thymidylate Synthase Gene in Colorectal Cancer Accompanied by Frequent Loss of Heterozygosity
The thymidylate synthase (TS) gene has a polymorphic repeated sequence in its 5′‐untranslated region. The repeat length is associated with TS protein expression, which suggests that we may be able to predict the efficacy of 5‐fluorouracil (S‐FU)‐based chemotherapy from a patient's TS genotype d...
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| Udgivet i: | Jpn J Cancer Res |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Publishing Ltd
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5926893/ https://ncbi.nlm.nih.gov/pubmed/12460463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2002.tb01227.x |
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