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Cloning of the 5’Upstream Region of the Rat p16 Gene and Its Role in Silencing

Hypermethylation of the 5’upstream region (5’region) of the human p16(CDKN2A) (p16) gene is known to cause silencing, which is involved in a wide range of human cancers. For the rat p16 gene, its 5’region has not been cloned, and it is uncertain whether surrogate use of exon la is adequate for analy...

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Bibliografski detalji
Izdano u:Jpn J Cancer Res
Glavni autori: Abe, Masanobu, Okochi, Eriko, Kuramoto, Takashi, Kaneda, Atsushi, Takato, Tsuyoshi, Sugimura, Takashi, Ushijima, Toshikazu
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2002
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926886/
https://ncbi.nlm.nih.gov/pubmed/12417039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2002.tb01211.x
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