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High-risk oral leukoplakia is associated with aberrant promoter methylation of multiple genes

BACKGROUND: Early detection of oral squamous cell carcinomas (OSCCs) is urgently needed to improve the prognosis and quality of life (QOL) of patients. Oral leukoplakias (OLs), known as the most common premalignant lesions in the oral cavity, often precede OSCCs. Especially, OLs with dysplasia are k...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Abe, Masanobu, Yamashita, Satoshi, Mori, Yoshiyuki, Abe, Takahiro, Saijo, Hideto, Hoshi, Kazuto, Ushijima, Toshikazu, Takato, Tsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891845/
https://ncbi.nlm.nih.gov/pubmed/27255271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2371-5
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