High-risk oral leukoplakia is associated with aberrant promoter methylation of multiple genes

BACKGROUND: Early detection of oral squamous cell carcinomas (OSCCs) is urgently needed to improve the prognosis and quality of life (QOL) of patients. Oral leukoplakias (OLs), known as the most common premalignant lesions in the oral cavity, often precede OSCCs. Especially, OLs with dysplasia are k...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Cancer
Main Authors: Abe, Masanobu, Yamashita, Satoshi, Mori, Yoshiyuki, Abe, Takahiro, Saijo, Hideto, Hoshi, Kazuto, Ushijima, Toshikazu, Takato, Tsuyoshi
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891845/
https://ncbi.nlm.nih.gov/pubmed/27255271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2371-5
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