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Mammary Carcinomas Induced in Human c‐Ha‐ras Proto‐oncogene Transgenic Rats Are Estrogen‐independent, but Responsive to d‐Limonene Treatment

We have previously shown that transgenic rats carrying three copies of the human c‐Ha‐ras proto‐ oncogene (Hras128) are highly susceptible to N‐methyl‐N‐nitrosourea (MNU) mammary carcino‐ genesis. All transgenic rats treated with 50 mg/kgMNU, i.v. at 50 days of age, were found to rapidly develop mul...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Asamoto, Makoto, Ota, Tomonori, Toriyama‐Baba, Hiroyasu, Hokaiwado, Naomi, Naito, Akihiro, Tsuda, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926874/
https://ncbi.nlm.nih.gov/pubmed/11802805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2002.tb01197.x
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