Transgenic Rats Carrying Human c‐Ha‐ras Proto‐oncogene Are Highly Susceptible to N‐Nitrosomethylbenzylamine Induction of Esophageal Tumorigenesis

A transgenic rat line carrying three copies of the human c‐Ha‐ras proto‐oncogene, including its own promoter region, has been established in our laboratory (Hras128 rats), and shown to be highly susceptible to induction of mammary and urinary bladder tumors. Mutation analysis of induced lesions indi...

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發表在:Jpn J Cancer Res
Main Authors: Asamoto, Makoto, Toriyama‐Baba, Hiroyasu, Ohnishi, Takamasa, Naito, Akihiro, Ota, Tomonori, Ando, Akira, Ochiya, Takahiro, Tsuda, Hiroyuki
格式: Artigo
語言:Inglês
出版: Blackwell Publishing Ltd 2002
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927067/
https://ncbi.nlm.nih.gov/pubmed/12149139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2002.tb01315.x
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