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Transgenic Rats Carrying Human c‐Ha‐ras Proto‐oncogene Are Highly Susceptible to N‐Nitrosomethylbenzylamine Induction of Esophageal Tumorigenesis

A transgenic rat line carrying three copies of the human c‐Ha‐ras proto‐oncogene, including its own promoter region, has been established in our laboratory (Hras128 rats), and shown to be highly susceptible to induction of mammary and urinary bladder tumors. Mutation analysis of induced lesions indi...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Asamoto, Makoto, Toriyama‐Baba, Hiroyasu, Ohnishi, Takamasa, Naito, Akihiro, Ota, Tomonori, Ando, Akira, Ochiya, Takahiro, Tsuda, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927067/
https://ncbi.nlm.nih.gov/pubmed/12149139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2002.tb01315.x
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