Enhancement by Cigarette Smoke Exposure of 2‐Amino‐3,8‐dimethylimidazo[4,5‐ f]quinoxaline‐induced Rat Hepatocarcinogenesis in Close Association with Elevation of Hepatic CYP1A2

The modifying effects of cigarette smoke (CS) exposure on a heterocyclic amine (HCA) 2‐amino‐3,8‐dimethylimidazo[4,5‐f]quinoxaline (MeIQx)‐induced carcinogenesis were investigated in male F344 rats. Groups 1 and 2 were fed MeIQx at a dose of 300 ppm, and simultaneously received CS and sham smoke (SS...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Nishikawa, Akiyoshi, Furukawa, Fumio, Miyauchi, Makoto, Son, Hwa‐Young, Okazaki, Kazushi, Koide, Akihiro, Mori, Yukio, Hirose, Masao
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2002
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926869/
https://ncbi.nlm.nih.gov/pubmed/11802804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2002.tb01196.x
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