Phage Display Cloning and Characterization of Monoclonal Antibody Genes and Recombinant Fab Fragment against the CD98 Oncoprotein

The Fab gene of anti‐CD98 heavy chain (h.c.) monoclonal antibody (mAb) HBJ127 was cloned and expressed as a recombinant Fab (rFab) fragment by means of a phage display system. The variable heavy and light chain genes of HBJ127 were found to be derived from VOx‐1 and IgVk8‐30 germline, respectively....

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Itoh, Kunihiko, Inoue, Kazuyuki, Hirooka, Kazumi, Maruyama, Kumiko, Ohkawa, Mayumi, Matsui, Kazuhiro, Tada, Hitoshi, Enomoto, Takemi, Hashimoto, Yoshiyuki, Suzuki, Toshio, Masuko, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2001
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926674/
https://ncbi.nlm.nih.gov/pubmed/11749697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2001.tb02155.x
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