Structure‐Activity Relationship of a Novel Group of Mammalian DNA Polymerase Inhibitors, Synthetic Sulfoquinovosylacylglycerols

We reported previously that sulfolipids in the sulfoquinovosylacylglycerol class from a fern and an alga are potent inhibitors of DNA polymerase α and β and potent anti‐neoplastic agents. In developing a procedure for chemical synthesis of sulfolipids, we synthesized many derivatives and stereoisome...

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Vydáno v:Jpn J Cancer Res
Hlavní autoři: Hanashima, Shinya, Mizushina, Yoshiyuki, Ohta, Keisuke, Yamazaki, Takayuki, Sugawara, Fumio, Sakaguchi, Kengo
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2000
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Rapid Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926251/
https://ncbi.nlm.nih.gov/pubmed/11050480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00887.x
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