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Prevention by Chitosan of Myelotoxicity, Gastrointestinal Toxicity and Immunocompetent Organic Toxicity Induced by 5‐Fluorouracil without Loss of Antitumor Activity in Mice

We examined the antitumor activity and side effects (myelotoxicity, immunocompetent organic toxicity and gastrointestinal toxicity) of combined treatment with the cancer chemotherapy drug 5‐fluorouracil (5‐FU) and dietary fiber chitosan in sarcoma 180‐bearing mice. 5‐FU (12.5 mg/kg×2/ day) plus chit...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Kimura, Yoshiyuki, Okuda, Hiromichi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926136/
https://ncbi.nlm.nih.gov/pubmed/10470290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1999.tb00813.x
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