Frameshift Mutation of the STK11 Gene in a Sporadic Gastrointestinal Cancer with Microsatellite Instability

Germline mutations of the STK11 gene lead to emergence of hamartomas in the gastrointestinal tract of patients with Peutz‐Jeghers syndrome, who bear an increased risk of malignancies of the gastrointestinal tract, genital tract, and other organs. We analyzed 80 sporadic colorectal cancers, six small...

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Vydáno v:Jpn J Cancer Res
Hlavní autoři: Nakagawa, Hidewaki, Koyama, Kumiko, Nakamori, Shoji, Kameyama, Masao, Imaoka, Shingi, Monden, Morito, Nakamura, Yusuke
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 1999
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926116/
https://ncbi.nlm.nih.gov/pubmed/10429655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1999.tb00794.x
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