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Mechanism of Oxidative DNA Damage Induced by a Heterocyclic Amine, 2‐Amino‐3,8‐dimethylimidazo[4,5‐f]quinoxaline
Adduct formation has been considered to be a major causal factor of DNA damage by carcinogenic heterocyclic amines. By means of experiments with (32)P‐labeled DNA fragments and an electrochemical detector coupled to a high‐pressure liquid chromatograph, we investigated whether the N‐hydroxy metaboli...
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| Udgivet i: | Jpn J Cancer Res |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Publishing Ltd
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5926070/ https://ncbi.nlm.nih.gov/pubmed/10359040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1999.tb00743.x |
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