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Interaction of Docetaxel (“Taxotere”) with Human P‐Glycoprotein

The interaction of docetaxel (“Taxotere”) with P‐glycoprotein (P‐gp) was examined using porcine kidney epithelial LLC‐PK(1) and LLC‐GA5‐COL150 cells, overexpressing human P‐gp selectively on the apical plasma membrane by transfection of human MDR1cDNA into the LLC‐PK(1) cells. The basal‐to‐apical tr...

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Dettagli Bibliografici
Pubblicato in:Jpn J Cancer Res
Autori principali: Shirakawa, Katsuro, Takara, Kohji, Tanigawara, Yusuke, Aoyama, Nobuo, Kasuga, Masato, Komada, Fusao, Sakaeda, Toshiyuki, Okumura, Katsuhiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926029/
https://ncbi.nlm.nih.gov/pubmed/10665657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1999.tb00723.x
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