Enhancement of the catalytic activity of Isopentenyl diphosphate isomerase (IDI) from Saccharomyces cerevisiae through random and site-directed mutagenesis

BACKGROUND: Lycopene is a terpenoid pigment that has diverse applications in the food and medicine industries. A prospective approach for lycopene production is by metabolic engineering in microbial hosts, such as Escherichia coli. Isopentenyl diphosphate isomerase (IDI, E.C. 5.3.3.2) is one of the...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Chen, Hailin, Li, Meijie, Liu, Changqing, Zhang, Haibo, Xian, Mo, Liu, Huizhou
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5925831/
https://ncbi.nlm.nih.gov/pubmed/29712558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-018-0913-z
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