Krüppel-like factor 4 (KLF4) induces mitochondrial fusion and increases spare respiratory capacity of human glioblastoma cells

Krüppel-like factor 4 (KLF4) is a zinc finger transcription factor critical for the regulation of many cellular functions in both normal and neoplastic cells. Here, using human glioblastoma cells, we investigated KLF4's effects on cancer cell metabolism. We found that forced KLF4 expression pro...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Wang, Shuyan, Shi, Xiaohai, Wei, Shuang, Ma, Ding, Oyinlade, Olutobi, Lv, Sheng-Qing, Ying, Mingyao, Zhang, Yu Alex, Claypool, Steven Michael, Watkins, Paul, Xia, Shuli
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2018
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5925822/
https://ncbi.nlm.nih.gov/pubmed/29507094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001323
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