Krüppel-like factor 4 (KLF4) induces mitochondrial fusion and increases spare respiratory capacity of human glioblastoma cells

Krüppel-like factor 4 (KLF4) is a zinc finger transcription factor critical for the regulation of many cellular functions in both normal and neoplastic cells. Here, using human glioblastoma cells, we investigated KLF4's effects on cancer cell metabolism. We found that forced KLF4 expression pro...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Wang, Shuyan, Shi, Xiaohai, Wei, Shuang, Ma, Ding, Oyinlade, Olutobi, Lv, Sheng-Qing, Ying, Mingyao, Zhang, Yu Alex, Claypool, Steven Michael, Watkins, Paul, Xia, Shuli
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2018
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5925822/
https://ncbi.nlm.nih.gov/pubmed/29507094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001323
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