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Structural basis for the catalytic mechanism and α-ketoglutarate cooperativity of glutamate dehydrogenase

Glutamate dehydrogenase (GDH) is a key enzyme connecting carbon and nitrogen metabolism in all living organisms. Despite extensive studies on GDHs from both prokaryotic and eukaryotic organisms in the last 40 years, the structural basis of the catalytic features of this enzyme remains incomplete. Th...

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Vydáno v:J Biol Chem
Hlavní autoři: Prakash, Prem, Punekar, Narayan S., Bhaumik, Prasenjit
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5925808/
https://ncbi.nlm.nih.gov/pubmed/29540480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000149
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