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Carbohydrate-polypeptide contacts in the antibody receptor CD16A identified through solution NMR spectroscopy

Asparagine-linked carbohydrates (N-glycans) are a common modification of eukaryotic proteins that confer multiple properties including the essential stabilization of therapeutic monoclonal antibodies. Here we present a rapid and efficient strategy to identify N-glycans that contact polypeptide resid...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Subedi, Ganesh P., Falconer, Daniel J., Barb, Adam W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5925738/
https://ncbi.nlm.nih.gov/pubmed/28613884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00392
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