Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80

N-terminal (Nt) acetylation is a major protein modification catalyzed by N-terminal acetyltransferases (NATs). Methionine acidic N termini, including actin, are cotranslationally Nt acetylated by NatB in all eukaryotes, but animal actins containing acidic N termini, are additionally posttranslationa...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Goris, Marianne, Magin, Robert S., Foyn, Håvard, Myklebust, Line M., Varland, Sylvia, Ree, Rasmus, Drazic, Adrian, Bhambra, Parminder, Støve, Svein I., Baumann, Markus, Haug, Bengt Erik, Marmorstein, Ronen, Arnesen, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924903/
https://ncbi.nlm.nih.gov/pubmed/29581307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719251115
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