Crystal structure of the Golgi-associated human N-alpha acetyltransferase 60 reveals the molecular determinants for substrate-specific acetylation

N-terminal acetylation is a common and important protein modification catalysed by N-terminal acetyltransferases (NATs). Six human NATs (NatA-NatF) contain one catalytic subunit each, Naa10-Naa60, respectively. In contrast to the ribosome associated NatA-NatE, NatF/Naa60 specifically associates with...

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Bibliographic Details
Published in:Structure
Main Authors: Støve, Svein Isungset, Magin, Robert S., Foyn, Håvard, Haug, Bengt Erik, Marmorstein, Ronen, Arnesen, Thomas
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938767/
https://ncbi.nlm.nih.gov/pubmed/27320834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.04.020
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