Targeting the miR-665-3p-ATG4B-autophagy axis relieves inflammation and apoptosis in intestinal ischemia/reperfusion

Autophagy is an essential cytoprotective response against pathologic stresses that selectively degrades damaged cellular components. Impaired autophagy contributes to organ injury in multiple diseases, including ischemia/reperfusion (I/R), but the exact mechanism by which impaired autophagy is regul...

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Vydáno v:Cell Death Dis
Hlavní autoři: Li, Zhenlu, Wang, Guangzhi, Feng, Dongcheng, Zu, Guo, Li, Yang, Shi, Xue, Zhao, Yan, Jing, Huirong, Ning, Shili, Le, Weidong, Yao, Jihong, Tian, Xiaofeng
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924757/
https://ncbi.nlm.nih.gov/pubmed/29706629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0518-9
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