miR-30b inhibits autophagy to alleviate hepatic ischemia-reperfusion injury via decreasing the Atg12-Atg5 conjugate

AIM: To explore the role and potential mechanism of miR-30b regulation of autophagy in hepatic ischemia-reperfusion injury (IRI). METHODS: An animal model of hepatic IRI was generated in C57BL/6 mice. For in vitro studies, AML12 cells were immersed in mineral oil for 1 h and then cultured in complet...

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Bibliografiske detaljer
Udgivet i:World J Gastroenterol
Main Authors: Li, Shi-Peng, He, Jin-Dan, Wang, Zhen, Yu, Yao, Fu, Shu-Yu, Zhang, Hai-Ming, Zhang, Jian-Jun, Shen, Zhong-Yang
Format: Artigo
Sprog:Inglês
Udgivet: Baishideng Publishing Group Inc 2016
Fag:
Basic Study
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858632/
https://ncbi.nlm.nih.gov/pubmed/27182160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v22.i18.4501
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