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Sensing microbial viability through bacterial RNA augments T follicular helper cell and antibody responses
Live vaccines historically afford superior protection, yet the cellular and molecular mechanisms mediating protective immunity remain unclear. Here we found that vaccination of mice with live, but not dead, Gram-negative bacteria heightened follicular T helper cell (Tfh) differentiation, germinal ce...
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| Publicado no: | Immunity |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5924674/ https://ncbi.nlm.nih.gov/pubmed/29548673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.02.015 |
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