STING senses Microbial Viability to Orchestrate Stress-Mediated Autophagy of the Endoplasmic Reticulum

Constitutive cell-autonomous immunity in metazoans predates interferon-inducible immunity and comprises primordial innate defense. Phagocytes mobilize interferon-inducible responses upon engagement of well-characterized signaling pathways by pathogen-associated molecular patterns (PAMPs). The signal...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Moretti, Julien, Roy, Soumit, Bozec, Dominique, Martinez, Jennifer, Chapman, Jessica R., Ueberheide, Beatrix, Lamming, Dudley W., Chen, Zhijian J., Horng, Tiffany, Yeretssian, Garabet, Green, Douglas R., Blander, J. Magarian
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811766/
https://ncbi.nlm.nih.gov/pubmed/29056340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.09.034
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