Stress Signaling JNK2 Crosstalk with CaMKII Underlies Enhanced Atrial Arrhythmogenesis

RATIONALE: Atrial fibrillation (AF) is the most common arrhythmia and advanced age is an inevitable and predominant AF risk factor. However, the mechanisms that couple aging and AF propensity remain unclear, making targeted therapeutic interventions unattainable. OBJECTIVE: To explore the functional...

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Pubblicato in:Circ Res
Autori principali: Yan, Jiajie, Zhao, Weiwei, Thomson, Justin K., Gao, Xianlong, DeMarco, Dominic M., Carrillo, Elena, Chen, Biyi, Wu, Xiaomin, Ginsburg, Kenneth S., Bakhos, Mamdouh, Bers, Donald M., Anderson, Mark E., Song, Long-Sheng, Fill, Michael, Ai, Xun
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924593/
https://ncbi.nlm.nih.gov/pubmed/29352041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.312536
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