Stress Signaling JNK2 Crosstalk with CaMKII Underlies Enhanced Atrial Arrhythmogenesis

RATIONALE: Atrial fibrillation (AF) is the most common arrhythmia and advanced age is an inevitable and predominant AF risk factor. However, the mechanisms that couple aging and AF propensity remain unclear, making targeted therapeutic interventions unattainable. OBJECTIVE: To explore the functional...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Circ Res
Prif Awduron: Yan, Jiajie, Zhao, Weiwei, Thomson, Justin K., Gao, Xianlong, DeMarco, Dominic M., Carrillo, Elena, Chen, Biyi, Wu, Xiaomin, Ginsburg, Kenneth S., Bakhos, Mamdouh, Bers, Donald M., Anderson, Mark E., Song, Long-Sheng, Fill, Michael, Ai, Xun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924593/
https://ncbi.nlm.nih.gov/pubmed/29352041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.312536
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