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Gene Therapy for Chronic HBV—Can We Eliminate cccDNA?

Chronic infection with the hepatitis B virus (HBV) is a global health concern and accounts for approximately 1 million deaths annually. Amongst other limitations of current anti-HBV treatment, failure to eliminate the viral covalently closed circular DNA (cccDNA) and emergence of resistance remain t...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Bloom, Kristie, Maepa, Mohube Betty, Ely, Abdullah, Arbuthnot, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924549/
https://ncbi.nlm.nih.gov/pubmed/29649127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9040207
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