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Homing in: mechanisms of substrate targeting by protein kinases
Protein phosphorylation is the most common reversible posttranslational modification in eukaryotes. Humans have over 500 protein kinases, of which more than a dozen are established targets for anti-cancer drugs. All kinases share a structurally similar catalytic domain, yet each one is uniquely posi...
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| Publicado no: | Trends Biochem Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5923429/ https://ncbi.nlm.nih.gov/pubmed/29544874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2018.02.009 |
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