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Bayesian nonparametric discovery of isoforms and individual specific quantification
Most human protein-coding genes can be transcribed into multiple distinct mRNA isoforms. These alternative splicing patterns encourage molecular diversity, and dysregulation of isoform expression plays an important role in disease etiology. However, isoforms are difficult to characterize from short-...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5923247/ https://ncbi.nlm.nih.gov/pubmed/29703885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03402-w |
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