IL-31 is crucial for induction of pruritus, but not inflammation, in contact hypersensitivity

IL-31, which is a member of the IL-6 family of cytokines, is produced mainly by activated CD4(+) T cells, in particular activated Th2 cells, suggesting a contribution to development of type-2 immune responses. IL-31 was reported to be increased in specimens from patients with atopic dermatitis, and...

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Publicat a:Sci Rep
Autors principals: Takamori, Ayako, Nambu, Aya, Sato, Keiko, Yamaguchi, Sachiko, Matsuda, Kenshiro, Numata, Takafumi, Sugawara, Takeru, Yoshizaki, Takamichi, Arae, Ken, Morita, Hideaki, Matsumoto, Kenji, Sudo, Katsuko, Okumura, Ko, Kitaura, Jiro, Matsuda, Hiroshi, Nakae, Susumu
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5923199/
https://ncbi.nlm.nih.gov/pubmed/29703903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25094-4
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