Intragastric Administration of Lactobacillus plantarum and 2,2′-Dithiodipyridine-Inactivated Simian Immunodeficiency Virus (SIV) Does Not Protect Indian Rhesus Macaques from Intrarectal SIV Challenge or Reduce Virus Replication after Transmission

A major obstacle to development of an effective AIDS vaccine is that along with the intended beneficial responses, the immunization regimen may activate CD4(+) T cells that can facilitate acquisition of human immunodeficiency virus (HIV) by serving as target cells for the virus. Lu et al. (W. Lu et...

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Udgivet i:J Virol
Main Authors: Carnathan, Diane G., Mackel, Joseph J., Sweat, Shelby L., Enemuo, Chiamaka A., Gebru, Etse H., Dhadvai, Pallavi, Gangadhara, Sailaja, Hicks, Sakeenah, Vanderford, Thomas H., Amara, Rama R., Esparza, José, Lu, Wei, Andrieu, Jean-Marie, Silvestri, Guido
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5923080/
https://ncbi.nlm.nih.gov/pubmed/29491157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02030-17
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