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Lipid Biosynthesis Coordinates a Mitochondrial-to-Cytosolic Stress Response
Defects in mitochondrial metabolism have been increasingly linked with age-onset protein-misfolding dieases such as Alzheimer’s, Parkinson’s, and Huntington’s. In response to protein-folding stress, compartment-specific unfolded protein responses (UPRs) within the ER, mitochondria, and cytosol work...
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| 發表在: | Cell |
|---|---|
| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5922983/ https://ncbi.nlm.nih.gov/pubmed/27610574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.08.027 |
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