Lipid Biosynthesis Coordinates a Mitochondrial-to-Cytosolic Stress Response

Defects in mitochondrial metabolism have been increasingly linked with age-onset protein-misfolding dieases such as Alzheimer’s, Parkinson’s, and Huntington’s. In response to protein-folding stress, compartment-specific unfolded protein responses (UPRs) within the ER, mitochondria, and cytosol work...

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Gepubliceerd in:Cell
Hoofdauteurs: Kim, Hyun-Eui, Grant, Ana Rodrigues, Simic, Milos S., Kohnz, Rebecca A., Nomura, Daniel K., Durieux, Jenni, Riera, Celine E., Sanchez, Melissa, Kapernick, Erik, Wolff, Suzanne, Dillin, Andrew
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922983/
https://ncbi.nlm.nih.gov/pubmed/27610574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.08.027
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