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On the role of extrinsic noise in microRNA-mediated bimodal gene expression

Several studies highlighted the relevance of extrinsic noise in shaping cell decision making and differentiation in molecular networks. Bimodal distributions of gene expression levels provide experimental evidence of phenotypic differentiation, where the modes of the distribution often correspond to...

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Détails bibliographiques
Publié dans:PLoS Comput Biol
Auteurs principaux: Del Giudice, Marco, Bo, Stefano, Grigolon, Silvia, Bosia, Carla
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922620/
https://ncbi.nlm.nih.gov/pubmed/29664903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006063
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