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On the role of extrinsic noise in microRNA-mediated bimodal gene expression

Several studies highlighted the relevance of extrinsic noise in shaping cell decision making and differentiation in molecular networks. Bimodal distributions of gene expression levels provide experimental evidence of phenotypic differentiation, where the modes of the distribution often correspond to...

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Publicat a:PLoS Comput Biol
Autors principals: Del Giudice, Marco, Bo, Stefano, Grigolon, Silvia, Bosia, Carla
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922620/
https://ncbi.nlm.nih.gov/pubmed/29664903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006063
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