Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs

Invasive fungal infections caused by the pathogen Candida albicans have transitioned from a rare curiosity to a major cause of human mortality. This is in part due to the emergence of resistance to the limited number of antifungals available to treat fungal infections. Azoles function by targeting t...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Mount, Harley O’Connor, Revie, Nicole M., Todd, Robert T., Anstett, Kaitlin, Collins, Cathy, Costanzo, Michael, Boone, Charles, Robbins, Nicole, Selmecki, Anna, Cowen, Leah E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922528/
https://ncbi.nlm.nih.gov/pubmed/29702647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007319
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