Beauvericin Potentiates Azole Activity via Inhibition of Multidrug Efflux, Blocks Candida albicans Morphogenesis, and Is Effluxed via Yor1 and Circuitry Controlled by Zcf29

Invasive fungal infections are a leading cause of human mortality. Effective treatment is hindered by the rapid emergence of resistance to the limited number of antifungal drugs, demanding new strategies to treat life-threatening fungal infections. Here, we explore a powerful strategy to enhance ant...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Shekhar-Guturja, Tanvi, Tebung, Walters Aji, Mount, Harley, Liu, Ningning, Köhler, Julia R., Whiteway, Malcolm, Cowen, Leah E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119031/
https://ncbi.nlm.nih.gov/pubmed/27736764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01959-16
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