Glypican-1 is enriched in circulating-exosomes in pancreatic cancer and correlates with tumor burden

BACKGROUND: Glypican-1 (GPC1) is expressed in pancreatic ductal adenocarcinoma (PDAC) cells and adjacent stromal fibroblasts. Recently, GPC1 circulating exosomes (crExos) have been shown to be able to detect early stages of PDAC. In this study, we investigated the usefulness of crExos GPC1 as a biom...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Frampton, Adam E., Prado, Mireia Mato, López-Jiménez, Elena, Fajardo-Puerta, Ana Belen, Jawad, Zaynab A.R., Lawton, Phillip, Giovannetti, Elisa, Habib, Nagy A., Castellano, Leandro, Stebbing, Justin, Krell, Jonathan, Jiao, Long R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922373/
https://ncbi.nlm.nih.gov/pubmed/29721179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24873
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