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Exosomal microRNA predicts and protects against severe bronchopulmonary dysplasia in extremely premature infants

Premature infants are at high risk for developing bronchopulmonary dysplasia (BPD), characterized by chronic inflammation and inhibition of lung development, which we have recently identified as being modulated by microRNAs (miRNAs) and alterations in the airway microbiome. Exosomes and exosomal miR...

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Pubblicato in:JCI Insight
Autori principali: Lal, Charitharth Vivek, Olave, Nelida, Travers, Colm, Rezonzew, Gabriel, Dolma, Kalsang, Simpson, Alexandra, Halloran, Brian, Aghai, Zubair, Das, Pragnya, Sharma, Nirmal, Xu, Xin, Genschmer, Kristopher, Russell, Derek, Szul, Tomasz, Yi, Nengjun, Blalock, J. Edwin, Gaggar, Amit, Bhandari, Vineet, Ambalavanan, Namasivayam
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922295/
https://ncbi.nlm.nih.gov/pubmed/29515035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93994
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