Calnexin is necessary for T cell transmigration into the central nervous system

In multiple sclerosis (MS), a demyelinating inflammatory disease of the CNS, and its animal model (experimental autoimmune encephalomyelitis; EAE), circulating immune cells gain access to the CNS across the blood-brain barrier to cause inflammation, myelin destruction, and neuronal damage. Here, we...

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Опубликовано в: :JCI Insight
Главные авторы: Jung, Joanna, Eggleton, Paul, Robinson, Alison, Wang, Jessica, Gutowski, Nick, Holley, Janet, Newcombe, Jia, Dudek, Elzbieta, Paul, Amber M., Zochodne, Douglas, Kraus, Allison, Power, Christopher, Agellon, Luis B., Michalak, Marek
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922283/
https://ncbi.nlm.nih.gov/pubmed/29515033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.98410
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