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Neoplastic Transformation of Rat Colon Epithelial Cells by Expression of Activated Human K‐ras

Somatic mutations of the K‐ras oncogene play an important role in colorectal carcinogenesis. We determined whether rat colon epithelial cells could be transformed by introducing retroviruses carrying the activated human K‐ras oncogene alone. Primary epithelial cells from the rat distal colon were in...

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Bibliografski detalji
Izdano u:Jpn J Cancer Res
Glavni autori: Sugiyama, Kenji, Otori, Kazuhiko, Esumi, Hiroyasu
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 1998
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921874/
https://ncbi.nlm.nih.gov/pubmed/9703359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1998.tb03263.x
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