Conditional knockout of N-Myc and STAT interactor disrupts normal mammary development and enhances metastatic ability of mammary tumors

The process of organ development requires a delicate balance between cellular plasticity and differentiation. This balance is disrupted in cancer initiation and progression. N-Myc and STAT interactor (NMI: human or Nmi: murine) has emerged as a relevant player in the etiology of breast cancer. Howev...

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Gepubliceerd in:Oncogene
Hoofdauteurs: Pruitt, Hawley C., Metge, Brandon J., Weeks, Shannon E., Chen, Dongquan, Wei, Shi, Kesterson, Robert A., Shevde, Lalita A., Samant, Rajeev S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921859/
https://ncbi.nlm.nih.gov/pubmed/29326438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-017-0037-7
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