Disruption of STAT5A and NMI signaling axis leads to ISG20-driven metastatic mammary tumors

Molecular dynamics of developmental processes are repurposed by cancer cells to support cancer initiation and progression. Disruption of the delicate balance between cellular differentiation and plasticity during mammary development leads to breast cancer initiation and metastatic progression. STAT5...

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Udgivet i:Oncogenesis
Main Authors: Alsheikh, Heba Allah M., Metge, Brandon J., Pruitt, Hawley C., Kammerud, Sarah C., Chen, Dongquan, Wei, Shi, Shevde, Lalita A., Samant, Rajeev S.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172570/
https://ncbi.nlm.nih.gov/pubmed/34078871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-021-00333-y
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