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Doxorubicin Redox Biology: Redox Cycling, Topoisomerase Inhibition, and Oxidative Stress

Doxorubicin (also called Adriamycin) is effective in treating a wide range of human cancers and currently considered as one of the most important drugs in cancer chemotherapeutics. The clinical use of doxorubicin is, however, associated with dosage-dependent cardiotoxicity and development of heart f...

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Detalhes bibliográficos
Publicado no:React Oxyg Species (Apex)
Main Authors: Zhu, Hong, Sarkar, Soumyadeep, Scott, Laura, Danelisen, Igor, Trush, Michael A., Jia, Zhenquan, Li, Y. Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921833/
https://ncbi.nlm.nih.gov/pubmed/29707645
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