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Effect of CPT‐11 on Lipid Peroxide Level in Mouse Tissues

We examined the effects of CPT‐11 on lipid peroxide level and glutathione peroxidase (GSHpx) activity as indices of the toxicity of this antitumor agent in mouse and rat tissues. After CPT‐11 (100 mg/kg, i.p.) administration, the lipid peroxide level in the heart increased 1.5 fold (mice) and 1.3 fo...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Sadzuka, Yasuyuki, Hirota, Sadao
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921459/
https://ncbi.nlm.nih.gov/pubmed/9247609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1997.tb00411.x
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